Reverse Remodeling in the Perspective of Decision-Making for Mitral Valve Repair with the MitraClip Running title: Rosenhek; Reverse Remodeling after MitraClip Therapy

Reverse remodeling in the perspective of decision making for mitral valve repair with the MitraClip.

Acute reverse annular remodeling during MitraClip® therapy predicts improved clinical outcome in heart failure patients: a 3D echocardiography study

BACKGROUND Transcatheter mitral valve repair (TMVR) has been shown to have acute effects on mitral valve geometry in patients with functional mitral regurgitation (FMR). This study investigates the impact of MitraClip® therapy-induced annular remodeling on clinical outcome and mitral regurgitation in heart failure patients. METHODS TMVR was performed successfully in 45 patients with FMR. In t...

Percutaneous mitral valve repair in the initial EVEREST cohort: evidence of reverse left ventricular remodeling.

BACKGROUND Percutaneous repair of mitral regurgitation (MR) permits examination of the effect of MR reduction without surgery and cardiopulmonary bypass on left ventricular (LV) dimensions and function. The goal of this analysis was to determine the extent of reverse remodeling at 12 months after successful percutaneous reduction of MR with the MitraClip device. METHODS AND RESULTS Of 64 pati...

Is MitraClip therapy really an alternative therapeutic option in functional mitral regurgitation when compared with ring annuloplasty?

A report by Taramasso et al. [1] describes their study of a new therapeutic modality, MitraClip therapy. There are multiple deficiencies in the article we would like to discuss. First, we disagree with the statement made in the title. The article actually compares the results of ‘downsized ring annuloplasty’ with MitraClip therapy in functional mitral regurgitation, but the title uses the misno...

Real-time left ventricular pressure-volume loops during percutaneous mitral valve repair with the MitraClip system.

BACKGROUND Percutaneous mitral valve repair with the MitraClip device has emerged as an alternative to surgery for treating severe mitral regurgitation. However, its effects on left ventricular loading conditions and contractility have not been investigated yet. METHODS AND RESULTS Pressure-volume loops were recorded throughout the MitraClip procedure using conductance catheter in 33 patients...